Metabolomic Analysis of Biochemical Changes in the Plasma of High-Fat Diet and Streptozotocin-Induced Diabetic Rats after Treatment with Isoflavones Extract of Radix Puerariae

Table 2

Effects of PTIF (421 mg/kg) on blood glucose in high-fat diet and STZ-induced diabetic rats (mmol/L).

Group		0 weeks	26 weeks	30 weeks	34 weeks	36 weeks
Normal	10	6.4 ± 0.5	6.8 ± 0.7	6.2 ± 0.5	6.4 ± 0.4	6.6 ± 0.6
Diabetic	10	6.5 ± 0.7	25.1 ± 2.9	25.0 ± 3.5	23.9 ± 4.0	25.1 ± 3.4
Diabetic + PTIF	9	6.2 ± 0.6	25.0 ± 2.1	23.6 ± 1.9	23.5 ± 3.0	22.5 ± 3.3

All data were expressed as mean ± SD. One-way analysis of variance (ANOVA) was used for significance analysis. indicate a significant difference as compared with normal rats.