Qi-Shen-Yi-Qi Dripping Pills Promote Angiogenesis of Ischemic Cardiac Microvascular Endothelial Cells by Regulating MicroRNA-223-3p Expression

Table 2

The differential expression of miRNAs in ischemia model group, QSYQ low-dose group, and normal group.

Gene	Fold change	value	Gene	Fold change	value
Upregulated miRNAs in ischemia model versus normal group
rno-miR-346	96.774	0.014	rno-miR-511-3p	3.294	0.000
rno-miR-142-5p	4.741	0.000	rno-miR-146a-5p	2.395	0.000
rno-miR-142-3p	4.533	0.000	rno-miR-155-5p	2.171	0.000
rno-miR-223-3p	4.299	0.000	rno-miR-494-5p	2.056	0.002
Downregulated miRNAs in ischemia model versus normal group
rno-miR-3596a	0.490	0.028	rno-miR-675-5p	0.415	0.042
rno-miR-802-5p	0.486	0.040	rno-miR-132-5p	0.392	0.000
rno-miR-140-5p	0.480	0.005	rno-miR-409b	0.383	0.008
rno-miR-132-3p	0.460	0.000	rno-miR-3596b	0.372	0.008
rno-miR-3560	0.447	0.004	rno-miR-300-3p	0.340	0.017
rno-miR-140-3p	0.440	0.001	rno-miR-10a-3p	0.337	0.035
rno-miR-330-3p	0.440	0.049	rno-miR-139-5p	0.312	0.003
rno-miR-212-3p	0.429	0.005
Upregulated miRNAs in QSYQ low-dose versus normal group
rno-miR-205	5.660	0.005	rno-miR-130b-5p	2.498	0.031
rno-miR-802-5p	5.562	0.043	rno-miR-551b-5p	2.279	0.048
rno-miR-539-3p	4.205	0.012	rno-miR-370-5p	2.198	0.006
rno-miR-3560	4.052	0.035	rno-miR-547-5p	2.156	0.013
rno-miR-93-3p	3.020	0.016	rno-miR-203a-3p	2.135	0.009
rno-miR-3549	2.656	0.025	rno-miR-291a-3p	2.039	0.030
rno-miR-222-3p	2.538	0.000	rno-let-7b-3p	2.034	0.024
rno-miR-760-5p	2.509	0.042	rno-miR-221-3p	2.008	0.000
Downregulated miRNAs in QSYQ low-dose versus normal group
rno-miR-186-3p	0.490	0.016	rno-miR-668	0.434	0.002
rno-miR-195-5p	0.484	0.007	rno-miR-300-3p	0.404	0.024
rno-miR-412-3p	0.471	0.008	rno-miR-221-5p	0.388	0.021
rno-miR-665	0.463	0.002	rno-miR-342-5p	0.371	0.038
rno-miR-336-5p	0.460	0.020	rno-miR-224-5p	0.340	0.003
rno-miR-674-3p	0.458	0.015	rno-miR-1843-5p	0.310	0.004
rno-miR-15b-5p	0.457	0.006	rno-miR-154-3p	0.303	0.003
rno-miR-342-3p	0.441	0.006	rno-miR-511-3p	0.254	0.001
rno-miR-212-3p	0.440	0.011	rno-miR-363-5p	0.192	0.001
Upregulated miRNAs in QSYQ low-dose versus ischemia model group
rno-miR-802-5p	11.437	0.031	rno-miR-547-5p	2.944	0.007
rno-miR-3560	9.074	0.020	rno-miR-192-5p	2.760	0.049
rno-miR-30c-1-3p	7.638	0.049	rno-miR-203a-3p	2.718	0.005
rno-miR-138-1-3p	6.987	0.036	rno-miR-200c-5p	2.622	0.022
rno-miR-205	6.898	0.004	rno-miR-25-5p	2.600	0.039
rno-miR-539-3p	5.222	0.012	rno-miR-505-5p	2.497	0.040
rno-miR-878	4.879	0.037	rno-miR-652-5p	2.487	0.035
rno-miR-93-3p	4.862	0.010	rno-miR-376b-3p	2.311	0.005
rno-miR-760-5p	4.789	0.018	rno-miR-410-5p	2.278	0.019
rno-miR-3549	4.685	0.009	rno-miR-23a-5p	2.209	0.019
rno-miR-743b-5p	4.681	0.034	rno-miR-134-3p	2.147	0.016
rno-miR-370-5p	3.662	0.003	rno-miR-299b-5p	2.134	0.038
rno-miR-132-5p	3.089	0.002	rno-miR-204-3p	2.125	0.019
Downregulated miRNAs in QSYQ low-dose versus ischemia model group
rno-miR-350	0.495	0.003	rno-miR-142-3p	0.300	0.000
rno-miR-338-5p	0.490	0.002	rno-miR-221-5p	0.279	0.008
rno-miR-154-3p	0.453	0.003	rno-miR-1843-5p	0.274	0.006
rno-miR-532-5p	0.435	0.002	rno-miR-146a-5p	0.265	0.000
rno-miR-336-5p	0.425	0.005	rno-miR-142-5p	0.210	0.000
rno-miR-15b-5p	0.417	0.006	rno-miR-363-5p	0.184	0.033
rno-miR-668	0.412	0.021	rno-miR-1843-5p	0.151	0.021
rno-miR-339-5p	0.396	0.000	rno-miR-223-3p	0.117	0.000
rno-miR-380-5p	0.374	0.031	rno-miR-511-3p	0.077	0.000
rno-miR-342-5p	0.369	0.029	rno-miR-346	0.074	0.018
rno-miR-674-3p	0.313	0.001