Research Article

Flavonoids Extraction from Propolis Attenuates Pathological Cardiac Hypertrophy through PI3K/AKT Signaling Pathway

Table 3

Echocardiography data after ISO-induced hypertrophy.

ā€‰SalineTFP
ā€‰CT ()ISO ()CT ()ISO ()

LVIDs (mm)2.09 0.313.01 0.282.11 0.212.25 0.35
LVIDd (mm)3.60 0.564.34 0.343.72 0.423.95 0.51
LVVs (L)14.29 3.1735.3 8.0418.35 4.2017.26 5.12
LVVd (L)54.28 10.6384.74 19.2863.89 13.1176.44 14.51
EF (%)75.23 8.3458.34 5.9171.28 11.5577.42 10.01
FS (%)43.20 6.0330.58 4.6739.94 6.9845.76 9.20
SV (L)39.99 11.5649.44 12.6445.55 13.1159.18 10.03

LVIDs, left ventricular internal diameter at systolic phase; LVIDd, left ventricular internal diameter at diastolic phase; LVVs, left ventricle end-systolic volume; LVVd, left ventricle end-diastolic volume; EF, ejection fraction; FS, fractional shortening; SV, stroke volume. All measurements are means SE. The data were analyzed by one-way ANOVA ( 0.05 compared to saline controls; 0.05 compared to ISO-induced saline-treated animals).