Antitumor Effect of Zhihuang Fuzheng Soft Capsules on Tumor-Bearing Mice

Table 6

Effect of ZFSC on CD4/CD8 value, NK cell activity, and PD1 and PDL1 in HT-1080 tumor-bearing mice.

Groups	Dose (mg/kg)	Number of animals	CD4/CD8	NK (nmol/L)	PD1 (pg/mL)	PDL1 (ng/L)
Model	—	8	0.087 ± 0.006	116.2 ± 12.8	82.0 ± 12.6	43.3 ± 8.8
Positive drug	5500	8	0.086 ± 0.009	117.8 ± 12.3	71.2 ± 9.0	47.2 ± 8.1
ZFSC	275	8	0.093 ± 0.011	100.4 ± 11.6	61.4 ± 9.8	36.0 ± 5.8
	550	8	0.092 ± 0.007	100.8 ± 24.0	69.0 ± 20.2	37.5 ± 11.1
	1100	8	0.096 ± 0.010	100.8 ± 12.9	66.1 ± 12.1	33.1 ± 5.0

Notes: and , compared with the model group.