Satkara (Citrus macroptera) Fruit Protects against Acetaminophen-Induced Hepatorenal Toxicity in Rats

Figure 7

Kidney sections from the experimental animals in (a) Group 1 (saline control) showing a normal morphology of renal parenchyma with well-defined glomeruli and tubules; (b) Group 2 (EECM control) showing a normal appearance of the renal parenchyma; (c and d) Group 3 (APAP control) demonstrating marked degeneration of the tubular epithelium (red arrow), vacuolization (green arrow), and severe glomerular necrosis (black arrow); and (e–h) Groups 4, 5, 6 (T 250, T 500, and T 1000 groups, resp.), and 7 (silymarin control) showing a remarkable degree of morphological preservation with only moderate to mild inflammation [magnification: 40x; scale bar: 20 μm].

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