Research Article

Satkara (Citrus macroptera) Fruit Protects against Acetaminophen-Induced Hepatorenal Toxicity in Rats

Table 2

The effects of EECM and APAP on serum CRE, urea, UA, Na+, K+, and Cl levels.

GroupParameters
CRE (mmol/L)Urea (mmol/L)UA (mmol/L)Na+ (mmol/L)K+ (mmol/L)Cl (mmol/L)

Saline control48.58 ± 2.384.79 ± 0.0740.33 ± 1.37138.67 ± 2.733.60 ± 0.18101.83 ± 1.33
EECM control45.39 ± 2.855.27 ± 0.4438.00 ± 2.00142.83 ± 4.404.05 ± 0.05103.00 ± 1.79
APAP control61.00 ± 2.286.94 ± 0.4158.50 ± 2.26150.33 ± 2.664.60 ± 0.2896.00 ± 3.35
T 25050.33 ± 2.886.42 ± 0.1251.33 ± 1.21143.17 ± 1.173.42 ± 0.3399.33 ± 1.51
T 50044.83 ± 1.725.75 ± 0.3639.92 ± 2.46140.70 ± 4.383.38 ± 0.12100.33 ± 3.20
T 100031.88 ± 1.104.99 ± 0.3037.95 ± 2.21141.80 ± 3.273.52 ± 0.08103.17 ± 3.13
Silymarin41.33 ± 2.255.77 ± 0.4927.50 ± 1.64140.67 ± 1.033.80 ± 0.09101.67 ± 1.37

The data are presented as the mean ± SD ().
In each column, each letter indicates a significant difference between two groups.
a indicates a significant difference between saline control and APAP control groups.
b indicates a significant difference between APAP control and T 250 groups.
c indicates a significant difference between APAP control and T 500 groups.
d indicates a significant difference between APAP control and T 1000 groups.
e indicates a significant difference between APAP control and silymarin groups.
f indicates a significant difference between T 250 and T 500 groups.
g indicates a significant difference between T 500 and T 1000 groups.
i indicates a significant difference between saline control and EECM control groups, respectively, at .