Cytotoxicity and Proapoptotic Effects of<i> Allium atroviolaceum</i> Flower Extract by Modulating Cell Cycle Arrest and Caspase-Dependent and<i> p53</i>-Independent Pathway in Breast Cancer Cell Lines

<div><i>Apoptosis study of MCF-7 and MDA-MB-231 cells exposed to FAA extract at IC25, IC50, and IC75 values</i>. The distribution of live cells and cells undergoing early apoptosis, late apoptosis, and necrosis was determined in (a) MCF7 and (b) MDA-MB-231 cells following treatment with FAA for 24, 48, and 72 h in comparison to the respective control, using Annexin-V-FITC and propidium iodide flow cytometric analysis. The values are presented as mean ± standard error of mean of three determinations.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 4: Cytotoxicity and Proapoptotic Effects of<i> Allium atroviolaceum</i> Flower Extract by Modulating Cell Cycle Arrest and Caspase-Dependent and<i> p53</i>-Independent Pathway in Breast Cancer Cell Lines 

Figure 4 | Cytotoxicity and Proapoptotic Effects of Allium atroviolaceum Flower Extract by Modulating Cell Cycle Arrest and Caspase-Dependent and p53-Independent Pathway in Breast Cancer Cell Lines 