Mechanisms of P-Glycoprotein Modulation by Semen Strychni Combined with Radix Paeoniae Alba

Table 1

Effect of RPAE on brucine transport in MDCK-MDR1 cells (, ).

Groups	(×10^−6 cm/s)	(×10^−6 cm/s)	ER
1 μg/mL SSE
1 μg/mL SSE + 1 μg/mL RPAE
1 μg/mL SSE + 3 μg/mL RPAE
1 μg/mL SSE + 6 μg/mL RPAE
1 μg/mL SSE + 100 μM verapamil

with contrast to the SSE 1 μg/mL group; with contrast to groups without verapamil.