Goreisan Inhibits Upregulation of Aquaporin 4 and Formation of Cerebral Edema in the Rat Model of Juvenile Hypoxic-Ischemic Encephalopathy

<table class="figure-group"><tr class="fig-image" id="a"><td><object data="https://static.hindawi.com/articles/ecam/volume-2017/3209219/figures/3209219.fig.005a.svgz" name="3209219.fig.005a" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(a) </b>Lesion side</td></tr><tr class="fig-image" id="b"><td><object data="https://static.hindawi.com/articles/ecam/volume-2017/3209219/figures/3209219.fig.005b.svgz" name="3209219.fig.005b" type="image/svg+xml"></object></td></tr><tr class="fig-caption"><td><b>(b) </b>Nonlesion side</td></tr></table>

<div><i>AQP4 mRNA expression levels</i>. Aquaporin 4 (AQP4) mRNA levels 36 h after surgery revealed the inhibitory effects of Goreisan. In the lesion side (a), the level of AQP4 mRNA of the nontreated group was significantly higher than that in the sham control, and the level of AQP4 mRNA in the Goreisan group was significantly lower than that of the nontreated group. In the nonlesion side (b), the level of AQP4 mRNA of the nontreated group was significantly higher than that of the sham control, and the level of AQP4 mRNA in the Goreisan group was significantly lower than that of the nontreated group.</div>

Evidence-Based Complementary and Alternative Medicine

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Figure 5

Figure 5: Goreisan Inhibits Upregulation of Aquaporin 4 and Formation of Cerebral Edema in the Rat Model of Juvenile Hypoxic-Ischemic Encephalopathy 