Central Administration of 1-Deoxynojirimycin Attenuates Hypothalamic Endoplasmic Reticulum Stress and Regulates Food Intake and Body Weight in Mice with High-Fat Diet-Induced Obesity

Figure 6

Effect of central administration of 1-deoxynojirimycin (DNJ) on leptin signaling in high-fat diet- (HFD-) fed mice. Effect of central administration of 50 μg/mL DNJ (1 μL) on leptin signaling pathways. The results of densitometric analysis are the means ± SDs ( per group). values (; ) indicate significant differences compared with vehicle (1 μL of distilled water; DW). HFD/DNJ (+/−), central administration of vehicle of HFD-fed group. HFD/DNJ (+/+), central administration of DNJ of HFD-fed group.