Antidiarrheal Activity of Dissotis multiflora (Sm) Triana (Melastomataceae) Leaf Extract in Wistar Rats and Subacute Toxicity Evaluation

Figure 3

Histological section of liver tissue (section stained with H&E, ×400). (A) Control with normal hepatocytes and centrilobular vein. (B) Liver of rats treated at the dose of 222.84 mg/kg of D. multiflora without capillary sinusoids dilations in both sexes and slight capillary sinusoids dilations in male treated rats. (C) Liver of rats treated at the dose of 445.68 mg/kg of D. multiflora with vascular congestion + slight capillary sinusoids dilations. (a) = male; (b) = female; CCLV = congestion of centrilobular vein; CLV = centrilobular vein; N = necrosis; H&E: Haematoxylin-Eosin.

(a)

(b)