Antihypercholesterolemic Effects of Fruit Aqueous Extract of Copernicia prunifera (Miller) H. E. Moore in Mice Diet-Induced Hypercholesterolemia

Figure 5

Histopathology images of liver and kidney hypercholesterolemic animals treated with APE. ((a)–(d)) Liver. (a) Standard diet, (b) hypercholesterolemic diet, (c) simvastatin, and (d) APE, aqueous fruit pulp extracts. Representative areas of inflammatory process consisting of neutrophils, macrophages, lymphocytes, and plasma cells (white arrows). ((e)–(g)) Liver. (e) Hypercholesterolemic diet, (f) simvastatin, and (g) APE, aqueous fruit pulp extracts. HE, fat droplets representing hepatic steatosis. ((h)–(k)) Kidney. (e) Standard diet, (f) hypercholesterolemic diet, (g) simvastatin, and (h) APE, aqueous fruit pulp extracts. HE, 200x.

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