Antihypercholesterolemic Effects of Fruit Aqueous Extract of Copernicia prunifera (Miller) H. E. Moore in Mice Diet-Induced Hypercholesterolemia

Table 6

Effects of APE/simvastatin treatment on serum total cholesterol and triglyceride levels in mice fed with HD for 30, 60, and 90 days.

Parameters (days)	SD	HD	SIMV	APE150	APE300
Cholesterol level
Baseline
30 days
60 days
90 days
Triglycerides level
Baseline
30 days
60 days
90 days
HDL level
Baseline
30 days
60 days
90 days
LDL level
Baseline
30 days
60 days
90 days

SD, standard diet; HD, hypercholesterolaemic diet; SIMV, simvastatin (20 mg/Kg/day, i.g.); TC, total cholesterol; TG, triglycerides. APE 150, APE 300 (aqueous fruit pulp extracts 150 and 300 mg/Kg/day, i.g.). Values are given as the mean ± SEM of 7 mice per group. To analyze the significance of the differences between the samples of authors used analysis of variance (ANOVA) followed by the Newman-Keuls comparison test, versus the SD group; versus HD group.