Research Article

Antihypercholesterolemic Effects of Fruit Aqueous Extract of Copernicia prunifera (Miller) H. E. Moore in Mice Diet-Induced Hypercholesterolemia

Table 7

Effects of APE on weight and total weight gain of mice submitted to the hypercholesterolemic diet.

GroupsInitial weight (g)Final weight (g)Total weight gain (g)Food intake (g/mice/day)
30 days60 days90 days

SD
HD
SIMV
APE 150
APE 300

SD, standard diet; HD, hypercholesterolaemic diet; SIMV, simvastatin (20 mg/Kg/day, i.g.); APE 150, APE 300 (aqueous fruit pulp extracts 150 and 300 mg/Kg/day, i.g.). Values are given as the mean ± SEM of 7 mice per group. To analyze the significance of the differences between the samples of authors used analysis of variance (ANOVA) followed by the Newman-Keuls comparison test, versus the SD group; versus HD group.