Research Article

Antihypercholesterolemic Effects of Fruit Aqueous Extract of Copernicia prunifera (Miller) H. E. Moore in Mice Diet-Induced Hypercholesterolemia

Table 8

Effects of APE on the relative liver weight, malondialdehyde in liver tissue and serum renal metabolites of mice submitted to the hypercholesterolemic diet.

ParametersSDHDSIMVAPE150APE300

RLW
MDA
AST
UREA
CREAT

SD, standard diet; HD, hypercholesterolaemic diet; SIMV, simvastatin (20 mg/Kg/day, i.g.); RLW, relative liver weight (relative liver weight = liver weight in percent of body weight); MDA, malondialdehyde; AST, aspartate aminotransferase; CREAT, creatinine. APE 150, APE 300 (aqueous fruit pulp extracts 150 and 300 mg/Kg/day, i.g.). Values are given as the mean ± SEM of 7 mice per group. To analyze the significance of the differences between the samples of authors used analysis of variance (ANOVA) followed by the Newman-Keuls comparison test, versus the SD group; versus HD group.