Research Article

Effect of Gelsemium elegans and Mussaenda pubescens, the Components of a Detoxification Herbal Formula, on Disturbance of the Intestinal Absorptions of Indole Alkaloids in Caco-2 Cells

Table 3

Effect of GM with or without verapamil on value of six indole alkaloids.

Indole alkaloidsGM+ verapamilGM (control group)
(cm/s × 10−6) (cm/s × 10−6) (cm/s × 10−6) (cm/s × 10−6)

Gelsemine
Humantenidine
Koumine
Gelsenicine
Gelsevirine
Humantenine

AP-BL is in the apical-to-basolateral direction and BL-AP is in the basolateral-to-apical direction. Data are expressed as mean ± SEM (). Significantly different from control of (). Significantly different from control of ().