Metabolomics Analysis for Defining Serum Biochemical Markers in Colorectal Cancer Patients with Qi Deficiency Syndrome or Yin Deficiency Syndrome

Table 3

Differential metabolites in the plasmas of CRC patients with YD compared with those with ND.

	VIP	mz	rt	Name	t-test	log2(YD/ND)
Upregulated	2.176	451	14.43	Diphosphate	0.000	2.926
	1.7	299	9.77	L-Isoleucine	0.000	1.946
	1.635	248	9.97	Glycine	0.000	1.818
	1.29	75	6.63	Lactic acid	0.007	1.319
	1.619	80	20.93	Arachidonic acid	0.001	1.292
	1.716	188	10.66	Serine	0.000	1.141
	1.612	370	22.69	1-Monopalmitoylglycerol	0.001	1.046
	1.563	60	7.73	Oxalic acid	0.001	1.033
	1.567	248	12.07	Aminomalonic acid	0.001	0.973
	1.295	84	16.32	N-α-Acetyl-L-lysine	0.006	0.877
	1.24	137	19.63	Oleic acid	0.009	0.818
	1.527	79	9.27	Urea	0.001	0.799
	1.061	192	13.92	Phenylalanine	0.027	0.679
	1.112	342	19.83	Stearic acid	0.020	0.674
	1.945	258	7.43	3-Oxaoct-4-en-11-imine	0.000	0.568
	1.029	179	16.66	Tyrosine	0.032	0.533
	1.576	155	11.92	GABA	0.001	0.510
	1.119	132	9.22	5-Hydroxycaproic acid	0.020	0.497
	1.018	97	18.08	Palmitic acid	0.034	0.462
	1.261	181	9.64	Phosphoric acid	0.008	0.380
	1.16	79	19.59	Linoleic acid	0.015	0.368
	1.23	57	27.67	Cholesterol	0.010	0.329
	1.164	155	11.58	Ethylamine	0.015	0.317
Downregulated	1.095	73	17.06	d-Glucose	0.022	−0.159
	1.079	75	17.06	Threose	0.025	−0.279
	1.161	321	16.98	d-Galactose	0.015	−0.517
	1.41	221	17.04	Mannose	0.003	−0.548
	1.19	205	16.89	Glucopyranose	0.013	−0.780
	1.754	206	17.70	β-D-Allopyranose	0.000	−1.190