Research Article

Gengnianchun, a Traditional Chinese Medicine, Enhances Oxidative Stress Resistance and Lifespan in Caenorhabditis elegans by Modulating daf-16/FOXO

Figure 2

The effect of GNC on oxidative stress resistance in C. elegans N2. Notes: GNC (0.0394, 0.394, 1.97, 3.94, or 7.88 mg/mL) and vehicle control (H2O)-pretreated wild-type worms were exposed to 10 mM Cr (VI). Survival after each treatment was assessed every 4 hours. GNC increased the mean and maximum survival times of worms under oxidative stress conditions in a dose-dependent manner.