Research Article
Gengnianchun, a Traditional Chinese Medicine, Enhances Oxidative Stress Resistance and Lifespan in Caenorhabditis elegans by Modulating daf-16/FOXO
Table 2
Survival time data under oxidative stress: effects of GNC treatment on wild-type and mutant C. elegans.
| Strain | Treatment (mg/mL) | Mean survival hours (±SEM) | Worms () | % change | value |
| N2 | Control | 25.83 ± 0.71 | 92 | 67 | <0.0001 | 3.94-GNC | 43.13 ± 1.17 | 90 | eat-2 (ad465) | Control | 35.69 ± 0.68 | 89 | 32 | <0.0001 | 3.94-GNC | 46.95 ± 0.90 | 91 | rsks-1 (ok1255) | Control | 37.39 ± 0.69 | 98 | 39 | <0.0001 | 3.94-GNC | 51.88 ± 1.02 | 99 | isp-1 (qm150) | Control | 20.40 ± 0.71 | 90 | 42 | <0.0001 | 3.94-GNC | 28.94 ± 0.72 | 94 | nuo-6 (qm200) | Control | 19.09 ± 0.57 | 92 | 47 | <0.0001 | 3.94-GNC | 28.04 ± 0.72 | 98 | glp-1 (e2144) | Control | 30.54 ± 0.62 | 95 | 24 | <0.0001 | 3.94-GNC | 37.92 ± 0.76 | 96 | daf-16 (mu86) | Control | 19.60 ± 0.63 | 90 | 0.06 | 0.2311 | 3.94-GNC | 20.74 ± 0.70 | 92 | daf-2 (e1370) | Control | 51.43 ± 1.56 | 91 | 28 | <0.0001 | 3.94-GNC | 65.87 ± 1.76 | 92 | age-1 (hx546) | Control | 45.82 ± 1.31 | 97 | 21 | <0.0001 | 3.94-GNC | 55.61 ± 1.51 | 92 |
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