Extracts of Salvia-Nelumbinis Naturalis Ameliorate Nonalcoholic Steatohepatitis via Inhibiting Gut-Derived Endotoxin Mediated TLR4/NF-κB Activation

Figure 8

The effect of SNN on TLR4 mediated NF-κB activation. The livers of the mice were collected, and the mRNA expressions of hepatic TLR2 (a) and TLR4 (b) were analyzed by qRT-PCR, and the key molecules in TLR4/NF-κB pathway were detected by Western blot (c and d). Data were presented as mean ± SE, n = 3–6, , , and versus Con mice; ^▲, ^▲▲ versus HF-DSS (NASH) mice.

(a)

(b)

(c)

(d)