Chloroform Extract of Artemisia annua L. Relaxes Mouse Airway Smooth Muscle

Figure 8

Effect of CEAA on the I/V relationship of BK channels in single channel recording in ASMCs. (a) Examples of BK channels in the absence (left) and the presence (middle) of CEAA (0.316 mg/ml) and the application of paxilline (right) measured from an outside-out patch recording at various membrane potentials from 0 to +60 mV with 20 mV increments. Arrows indicate the baseline (all channels in nonpermeant states). The upward current on baseline indicates channel opening. (b) Averaged NPo ratios/voltage and I/V relationships of BK channels were plotted in the absence and presence of CEAA (0.316 mg/ml), ; ; .

(a)

(b)