Evidence-Based Complementary and Alternative Medicine

Research Article

The Bioavailability and Pharmacokinetics of Silymarin SMEDDS Formulation Study in Healthy Thai Volunteers

Table 3

95% confidence interval (lower and upper mean) of the pharmacokinetic parameters of silybin after the oral administration of silymarin SMEDDS soft capsules.
Parameters95% Confidence Interval (lower and upper mean)
(ng/mL)536.63–1088.23
(ng.h/mL)489.64–827.96
(ng.h/mL)506.49–847.48
: maximum observed plasma concentration; : area under the plasma concentration versus time curve up to the last; : area under the plasma concentration versus time curve with the concentration extrapolated based on the elimination rate constant.