Research Article
The Bioavailability and Pharmacokinetics of Silymarin SMEDDS Formulation Study in Healthy Thai Volunteers
Table 4
Pharmacokinetic parameters of silybin after the oral administration ofsilymarin SMEDDS soft capsules compared with conventional capsules from the published study.
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Note. Published study conducted by Zhu and coworkers in 2013 [15]. Published study conducted by Brinda and coworkers in 2012 [16]. Median (range). : maximum observed plasma concentration; : area under the plasma concentration versus time curve up to the last; : area under the plasma concentration versus time curve with the concentration extrapolated based on the elimination rate constant; : time to ; N/A: not available. |