Capybara Oil Improves Hepatic Mitochondrial Dysfunction, Steatosis, and Inflammation in a Murine Model of Nonalcoholic Fatty Liver Disease

Figure 4

Mitochondrial functional evaluation in the liver of C57BL/6 mice treated with capybara oil. (a, b, c, and d) (a) represents high-resolution respirometry in liver cells. (b) Maximal ADP-stimulated respiratory rates (State 3) with substrates related to carbohydrate oxidation, (c) maximal ADP-stimulated respiratory rates (State 3) with substrates related to fatty acid oxidation, (d) respiratory control ratio (RCR), and calculated as State 3/State 4 ratios for CHO and FAs oxidation, respectively. Data are expressed as mean ± SEM. Statistical analyses were performed using a one-way ANOVA analysis of variance followed by Bonferroni test. (a) compared to CG group; compared to NAFLD group. (b) compared to CG group; compared to NAFLD group. (c) compared to CG group; compared to NAFLD group. (d) compared to CG group.

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