Prevention of Prostate Tumor Development by Stimulation of Antitumor Immunity Using a Standardized Herbal Extract (Deep Immune®) in TRAMP Mice

Table 4

Phenotypes of splenocytes from TRAMP mice before (onset group) or after 3-month treatment (both control and extract groups).

Phenotypes (%)	Onset	Control	Extract	value (onset versus control)	value (onset versus extract)	value (control versus extract)
CD4				0.2080	0.2714	0.7074
CD8				0.0043	0.1713	0.0474
CD45R/B220				0.0864	0.2539	0.1929
NK1.1				0.0031	0.4619	0.1549
Mac3				0.0001	0.3787	0.0872
CD11b				0.0177	0.6582	0.0579

Phenotypes of splenocytes (CD4: CD4⁺ T cells; CD8: CD8⁺ T cells; CD45R: B cells; NK1.1: NK cells; Mac3: macrophages; CD11b: DCs) were determined by FACS analysis. Data are presented as mean ± SEM in each group, and were compared using two-tailed -test.