Does Adjuvant Treatment with Chinese Herbal Medicine to Antidiabetic Agents Have Additional Benefits in Patients with Type 2 Diabetes? A System Review and Meta-Analysis of Randomized Controlled Trials
Table 1
Characteristics of included studies.
Study ID
Subjects (T/C)
Age (years) (T/C)
Diagnostic criteria
Intervention
Main outcome measures
Course of Treatment
Language of Publication
T
C
Zhang 2008
57/49
T:51±9 C: 51±10
1999 WHO
berberine+ Metformin
placebo+ Metformin
HbA1c FBG 2hPG
12 weeks
English
Tong 2013
292/107
T:54.4±7.7 C:54.5±7.6
1999 WHO
TM81+ Metformin
placebo+ Metformin
HbA1c FBG 2hPG
12 weeks
English
Ji2013a
164/160
T:54±9 C:54±8
1999 WHO
Xiaoke pills+ Glibenclamide
Glibenclamide
HbA1c FBG, 2hPG
48 weeks
English
Ji2013b
153/150
T:54±8 C:55±9
1999 WHO
Xiaoke pills+ Glibenclamide+ Metformin
Glibenclamide + Metformin
HbA1c FBG, 2hPG
48 weeks
English
Lian 2015
92/94
T:55.18±9.13 C:55.81±9.93
1999 WHO
Jinlida + Metformin
Placebo + Metformin
HbA1c FBG, 2hPG
12 weeks
English
Hu 2016
59/53
T:56.3±11.1 C:54.9±10.3
1999 WHO
Jian yu tang Kang + Metformin
Placebo + Metformin
HbA1c FBG, 2hPG
26 weeks
English
Xu 2014
52/41
T:55.06±7.49 C: 50.7±9.40
1999 WHO
Ge Gen Qin Lian+ Metformin
placebo+ Metformin
HbA1c FBG, 2hPG
12 weeks
English
Wangsh 2014
89/89
T:56.27±9.8 C:55. 78±9.17
1999 WHO
Tang ke+ Metformin
Placebo+ Metformin
HbA1c FBG, 2hPG
12 weeks
Chinese
Tong 2009
67/69
T:52.93±6.58 C:52.4±8.61
1999 WHO
TangMinling pills+ Metformin
Placebo+ Metformin
HbA1c FBG, 2hPG
12 weeks
Chinese
Lian 2011
40/39
T:53.3±6.98 C:56.4±9.00
1999 WHO
Tian Qi Jiang Tang + Metformin
Placebo + Metformin
HbA1c FBG, 2hPG
12 weeks
Chinese
Wang 2014
49/44
T:59.00±6.5 C:63.00±5.6
1999 WHO
Liuwei Dihuang Combined With Ginkgo Leaf+ Metformin
