Does Adjuvant Treatment with Chinese Herbal Medicine to Antidiabetic Agents Have Additional Benefits in Patients with Type 2 Diabetes? A System Review and Meta-Analysis of Randomized Controlled Trials

Table 4

Incidence of adverse events.

	Total events/total number		Risk ratio; (95% CI)
	Treatment	Control
Gastrointestinal reactions	6/1109	9/895	0.67(0.25,1.76)
Rash	1/1109	3/895	0.33(0.44,3.11)
Weakness	2/1109	2/895	1.00(0.15,6.87)
Weight loss	0/1109	1/895	0.33(0.01,8.02)
Frequently urination	1/1109	0/895	3.00(0.12,72.20)
Tinnitus	0/1109	2/895	0.20(0.01,4.08)
Genital swelling	0/1109	1/895	0.33(0.11,8.02)
Elevated blood white blood cell	0/1109	1/895	0.33(0.11,8.02)
Decreased hemoglobin	2/614	0/610	5.00(0.25,102.0)
Elevated urine white blood cell	1/614	1/610	1.00(0.06,15.62)
Total events	13	20
Incidence of any adverse event		Pooled rate ratio: 0.70 (0.37,1.29)