Research Article
Antimalarial Activity and Toxicological Assessment of Betula alnoides Extract against Plasmodium berghei Infections in Mice
Table 4
Biochemical parameters of the negative control group and the group treated with the aqueous extract of B. alnoides.
| Parameters | Negative control | 5000 mg/kg | Male | Female | Male | Female |
| Liver function tests | Total protein (g/L) | 4.30 ± 0.10 | 4.63 ± 0.13 | 4.47 ± 0.23 | 4.73 ± 0.07 | Albumin (g/L) | 2.69 ± 0.01 | 2.70 ± 0.00 | 2.69 ± 0.01 | 2.70 ± 0.10 | AST (U/L) | 138.87 ± 1.73 | 141.00 ± 1.00 | 137.28 ± 3.58 | 135.32 ± 2.54 | ALT (U/L) | 85.27 ± 0.17 | 85.60 ± 0.35 | 85.60 ± 0.98 | 85.43 ± 3.08 | ALP (U/L) | 81.13 ± 1.11 | 79.37 ± 0.41 | 80.13 ± 1.76 | 79.38 ± 0.51 |
| Kidney function tests | BUN (mg/dL) | 26.21 ± 0.97 | 26.00 ± 0.00 | 27.57 ± 1.58 | 23.50 ± 1.75 | Creatinine (mg/dL) | 0.13 ± 0.02 | 0.21 ± 0.03 | 0.14 ± 0.01 | 0.18 ± 0.02 |
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