Antimalarial Activity and Toxicological Assessment of Betula alnoides Extract against Plasmodium berghei Infections in Mice

Table 4

Biochemical parameters of the negative control group and the group treated with the aqueous extract of B. alnoides.

Parameters	Negative control		5000 mg/kg
	Male	Female	Male	Female
Liver function tests
Total protein (g/L)	4.30 ± 0.10	4.63 ± 0.13	4.47 ± 0.23	4.73 ± 0.07
Albumin (g/L)	2.69 ± 0.01	2.70 ± 0.00	2.69 ± 0.01	2.70 ± 0.10
AST (U/L)	138.87 ± 1.73	141.00 ± 1.00	137.28 ± 3.58	135.32 ± 2.54
ALT (U/L)	85.27 ± 0.17	85.60 ± 0.35	85.60 ± 0.98	85.43 ± 3.08
ALP (U/L)	81.13 ± 1.11	79.37 ± 0.41	80.13 ± 1.76	79.38 ± 0.51
Kidney function tests
BUN (mg/dL)	26.21 ± 0.97	26.00 ± 0.00	27.57 ± 1.58	23.50 ± 1.75
Creatinine (mg/dL)	0.13 ± 0.02	0.21 ± 0.03	0.14 ± 0.01	0.18 ± 0.02