Research Article

Novel Acaricidal Drug Fluazuron Causes Immunotoxicity via Selective Depletion of Lymphocytes T CD8

Table 2

Computational analysis of probable biological interactions for Fluazuron using the Way2Drug Platform [10] Associated with Genecards Databank [11].

TargetPredictionGenecards information

Cytokine production inhibitorActive------
DNA polymerase I inhibitorActive------
Increases expression of the ATG5 geneActiveProtein involved in the formation of the Autophagic Vesicle in Cell Death.
Reduces expression of the CCNC geneActiveCyclin protein involved in apoptosis routes.
Reduces IFNG gene expressionActiveγ Interferon protein, important mediator of the immune system.