Research Article
Sesamin, a Naturally Occurring Lignan, Inhibits Ligand-Induced Lipogenesis through Interaction with Liver X Receptor Alpha (LXRα) and Pregnane X Receptor (PXR)
Figure 3
Molecular docking analysis of T0901317 (T090) and sesamin (SSM) with LXRα. Superimposition of docking posed of compounds in the LXRα-binding pocket of 3D structure (PDB entry 1UHL). (a) Pose 3D structure of agonist T090 in the active site of LXRα ligand-binding domain. (b) Docking pose of SSM in the active site of LXRα ligand-binding domain.
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