Integrated Chinese Herbal Medicine and Western Medicine on the Survival in Patients with Colorectal Cancer: A Retrospective Study of Medical Records

Table 5

Effects of 10 most commonly used Chinese herbal medicine formulae on the survival of patients with colorectal cancer (N = 535).

Formula (n)	Unadjusted analysis			Adjusted analysis
	HR	95% CI		Adjusted HR	95% CI
Jia Wei Xiao Yao San
Not used(476)	1.00			1.00
Low dose (29)	0.77	0.40–1.51	0.446	0.40	0.20–0.79	0.009
High dose (30)	0.34	0.14–0.82	0.017	0.38	0.16–0.93	0.035
Liu wei Di huang Wan
Not used (503)	1.00			1.00
Low dose (16)	0.44	0.14–1.37	0.158	0.64	0.20–2.01	0.443
High dose (16)	0.12	0.02–0.89	0.038	0.18	0.02–1.28	0.086
Zhi Bai Di Huang Wan
Not used (507)	1.00			1.00
Low dose (15)	0.74	0.30–1.79	0.497	0.46	0.20–1.13	0.091
High dose (13)	0.15	0.02–1.09	0.061	0.15	0.02–1.05	0.056
Ban Xia Xie Xin Tang
Not used (500)	1.00			1.00
Low dose (19)	0.72	0.32–1.62	0.424	0.49	0.21–1.14	0.096
High dose (16)	0.41	0.13–1.28	0.126	0.32	0.10–1.00	0.049
Ping Wei San
Not used (475)	1.00			1.00
Low dose (41)	0.83	0.47–1.45	0.505	0.56	0.32–1.01	0.054
High dose (19)	0.45	0.17–1.20	0.110	0.31	0.11–0.84	0.022
Zhi Gan Cao Tang
Not used (508)	1.00			1.00
Low dose (13)	0.18	0.03–1.28	0.086	0.19	0.03–1.36	0.099
High dose (14)	0.45	0.14–1.40	0.165	0.48	0.15–1.50	0.204
Li Zhong Tang
Not used (491)	1.00			1.00
Low dose (20)	0.63	0.26–1.52	0.302	0.47	0.19–1.16	0.101
High dose (24)	0.42	0.17–1.03	0.057	0.50	0.20–1.22	0.130
Du Huo Ji Sheng Tang
Not used (527)	1.00			1.00
Low dose (2)	NC	NC	NC	NC	NC	NC
High dose (6)	0.31	0.04–2.20	0.240	0.47	0.07–3.38	0.453
Qui Pi Tang
Not used (500)	1.00			1.00
Low dose (17)	1.21	0.54–2.73	0.650	1.27	0.56–2.87	0.571
High dose (18)	0.78	0.34–1.75	0.544	0.26	0.11–0.59	0.001
Huo Xiang Zhen Qi San
Not used (494)	1.00			1.00
Low dose (22)	1.31	0.67–2.56	0.428	1.08	0.55–2.14	0.819
High dose (19)	0.48	0.18–1.29	0.145	0.66	0.24–1.78	0.407

CI: confidence interval; HR: hazards ratio; NC: not calculable.