A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action for the Rougui-Fuzi Herb Pair in the Treatment of Cardiocerebral Vascular Diseases

Table 1

The three centralities of 21 compounds were all higher than the average in C-T-D network.

MOL ID	Molecule name	Structure	Degree centrality (DC)	Betweenness centrality (BC)	Closeness centrality (CC)
MOL000675	Oleic acid		17	0.1394	0.4577
MOL002526	δ-Guaijene		8	0.0242	0.304
MOL000911	Terpilene		8	0.0248	0.3916
MOL000126	(−)-Nopinene		6	0.0398	0.4362
MOL000069	Palmitic acid		6	0.0332	0.3779
MOL000118	(L)-Alpha-terpineol		5	0.0119	0.3892
MOL000254	Eugenol		5	0.0297	0.4305
MOL003521	Isohomogenol		5	0.0083	0.3869
MOL000677	(1R, 4R)-4-Isopropyl-1,6-dimethyltetralin		5	0.0067	0.3916
MOL002392	Deltoin		5	0.0093	0.3916
MOL002417	Fuzitine		5	0.0086	0.3801
MOL000431	Coumarin		5	0.0127	0.3757
MOL003525	Pyruvophenone		5	0.0253	0.3631
MOL000198	(R)-Linalool		4	0.0075	0.3736
MOL000131	Linoleic acid		4	0.0181	0.414
MOL001393	Myristic acid		4	0.0146	0.3693
MOL000932	Alpha-farnesene		4	0.0121	0.3652
MOL000991	Cinnamaldehyde		4	0.0121	0.3652
MOL002295	Cinnamic acid		3	0.0141	0.4037
MOL000249	Methylcinnamate		3	0.0141	0.4037
MOL003531	3-Methoxycinnamaldehyde		3	0.0141	0.4037