A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action for the Rougui-Fuzi Herb Pair in the Treatment of Cardiocerebral Vascular Diseases

Table 2

The 7 pathways information of rougui-fuzi in treatment with CCVDs.

Pathways	Degree centrality (DC)	Betweenness centrality (BC)	Closeness centrality (CC)
Complement and coagulation cascades	7	0.5017	0.2381
Neuroactive ligand-receptor interaction	6	0.2193	0.1795
PI3K-Akt signaling pathway	6	0.5513	0.2518
Arachidonic acid metabolism	5	0.2185	0.2000
Cholesterol metabolism	4	0.1664	0.1515
PPAR signaling pathway	4	0.3479	0.1977
NF-kappa B signaling pathway	4	0.6673	0.2800