A Systems Pharmacology Approach for Identifying the Multiple Mechanisms of Action for the Rougui-Fuzi Herb Pair in the Treatment of Cardiocerebral Vascular Diseases

Table 3

8 key target proteins obtained by PPI network.

Gene name	Degree centrality (DC)	Betweenness centrality (BC)	Closeness centrality (CC)
PTGS2	14	0.2411	0.8500
INS	12	0.1764	0.7727
IL4	11	0.0701	0.7391
TLR4	11	0.0734	0.7391
F3	10	0.0361	0.7083
PLG	10	0.0361	0.7083
SERPINE1	10	0.0361	0.7083
F2	9	0.0275	0.6800