Huanglian Jiedu Decoction Exerts Antipyretic Effect by Inhibiting MAPK Signaling Pathway

Figure 7

HLJDD suppresses the expression of MAPK signaling pathway. (a) Western Blotting images of ERK, p-ERK, JNK, p-JNK, P38, p-P38, and GAPDH. (b) Relative p-ERK protein expression in hypothalamus tissue. (c) Relative p-JNK protein expression in hypothalamus tissue. (d) Relative p-P38 protein expression in hypothalamus tissue. <0.01 versus control group. ^##<0.01 versus model group. <0.05 versus control group. ^#<0.05 versus model group. Control: as a blank control group; model: intraperitoneal injection of LPS 100 μg/kg; HLJDD L: HLJDD low dose group (1.58 g/kg); HLJDD M: HLJDD medium dose group (3.15 g/kg); HLJDD H: HLJDD high dose group (6.30 g/kg).

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