Research Article

Antiplatelet and Antithrombotic Activities of Lespedeza cuneata via Pharmacological Inhibition of Integrin αIIbβ3, MAPK, and PI3K/AKT Pathways and FeCl3-Induced Murine Thrombosis

Figure 3

Antiplatelet activity of Lespedeza cuneata. Washed platelets were incubated for 1 min with varying concentrations of L. cuneata with 50%, 70%, and 100% EtOH and water extracts or vehicle (DMSO) along with 1 mM calcium chloride, stimulated with collagen for 5 min. The graph represents the mean ± SEM of at least three independent experiments. , , and compared with the agonist-treated group.