Intracellular Signalling by C-Peptide

Table 1

Signalling elements activated by C-peptide according to cell type studied (for abbreviations see text).

Cell type studied
Signalling element	Kidney tubular	Muscle	Fibroblasts	Endothelial	Erythrocytes	Neuroblastoma	CD4 + T Cells	Nerve
Na^+,K^+-ATPase	+				+			+
∼[Ca^2+]i	+			+
PKC	+		+
NO release		+		+
ERK	+	+	+	+
p38 MAPK				+
JNK	+
PLC	+
p90RSK		+
GSK3		+
PI3K	+	+		+		+	+
CREB				+
NF-κB	+		+			+
PPAR	+