]>Change in Long-Spacing Collagen in Descemet's Membrane of Diabetic Goto-Kakizaki Rats and Its Suppression by Antidiabetic Agents : Figure 8
818341.fig.008
Figure 8: Inhibition by antidiabetic agents of the formation of long-spacing collagen in 15-week-old GK rats. The rats were administered methylcellulose alone (GK-Control), nateglinide (GK-Nateglinide) or glibenclamide (GK-Glibenclamide) for 15 weeks, which agents were suspended in methylcellulose. The number of long-spacing collagen fibrils in the Descemet’s membrane was examined by electron microscopy. Data are presented as the m e a n ± S D ( 𝑛 = 4 ). GK, GK rats. * 𝑃 < . 0 5 , ** 𝑃 < . 0 1 .