Review Article
Therapeutics of Diabetes Mellitus: Focus on Insulin Analogues and Insulin Pumps
Table 3
CSII therapy in pediatric patients.
| | Current indications |
| | Recurrent severe hypoglycemia | | Wide fluctuations in blood glucose levels regardless of HbA1c | | Suboptimal diabetes control | | Microvascular complications and/or risk factors for macrovascular complications | | Good metabolic control but insulin regimen that compromises lifestyle (e.g., competitive athletes and needle phobia) | | Adolescents with eating disorders | | Children and adolescents with a pronounced dawn phenomenon | | Ketosis-prone individuals |
| | Advantages of CSII compared with MDI in children |
| | Easier and convenient adjustment of bolus insulin dose and nocturnal basal insulin dose | | Greater accuracy of insulin dosage | | Easier management of infectious illnesses and hyperglycemic episodes | | Quality of life improvement | | Less injections Less anxiety better compliance | | Flexibility of everyday activities |
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