Review Article

Maternal Obesity and Developmental Programming of Metabolic Disorders in Offspring: Evidence from Animal Models

Figure 2

Total body fat mass (%) as quantified by dual energy X-ray absorptiometry (DEXA) in adult (day 150) male and female rat offspring of HF-fed mothers. CON = offspring of control pregnancies, MHF = offspring of mothers fed an HF diet from weaning and throughout pregnancy and lactation, PLHF mothers fed a control diet until conception, and an HF diet throughout pregnancy and lactation. Note that a preconceptional HF diet did not confer an altered risk for obesity development over that of HF exposure during pregnancy and lactation alone. Data are means ± SEM, per group, * versus CON. Modified from Howie et al. [29].
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