Review Article

A Systematic Review of Ethanol and Fomepizole Use in Toxic Alcohol Ingestions

Table 3

Treatment and intubation data by EG and Me.

VariableEthylene glycolMethanol
EthanolFomepizoleBothEthanolFomepizoleBoth
(n = 215)(n = 65)(n = 15)(n = 505)(n = 81)(n = 18)

Regimen1(n = 146)(n = 59)(n = 5)(n = 251)(n = 74)(n = 13)
 Fomepizole
  Standard39%0%70.3%53.8%
  Other59%100%29.7%38.5%
 Ethanol
  Oral only2.7%20%11.1%0%
  IV only87.7%20%30.2%38.5%
  Oral and IV0.7%20%0.8%0%

Intubation(n = 33)(n = 15)(n = 3)(n = 153)(n = 12)(n = 7)
(% of total reported)
78.8%53.3%33.3%52.3%58.3%42.9%

Intubation after ADH blockade(n = 25)
(n = 8)
(n = 1)
(n = 19)
(n = 7)
(n = 3)
(% of intubated patients)16%12.5%0%15.8%0%66.7%

ME: methanol, EG: ethylene glycol, IV: intravenous, ADH: alcohol dehydrogenase.
Results are a combination of data from individual case data and aggregate data. n in bold at top of each column represents total number of patients in the group. n in each cell represents number of patients for whom data was present.
1Percentages do not total 100% because some cases did not describe the route of ethanol dose.