The Etiological Spectrum of Febrile Encephalopathy in Adult Patients: A Cross-Sectional Study from a Developing Country

Table 2

The comparison of the characteristics between patients with CNS infection and SAE.

	SAE	CNS infection	value	CNS infection with encephalopathy syndrome	value
Age, years (mean)	68.26	42.57	<0.001	48.12	<0.001
Underlying Conditions
Bedridden status	22 (33.8)	2 (1.3)	<0.001	2 (1.9)	<0.001
Dementia	11 (16.9)	4 (2.6)	<0.001	4 (3.7)	0.004
Diabetes (DM)	16 (24.6)	14 (9.1)	0.002	13 (12)	0.032
HTN/IHD	26 (40)	31 (20.1)	0.002	30 (27.8)	0.096
CVA	15 (23.1)	7 (4.5)	<0.001	7 (6.5)	0.002
Psychiatric disorder	5 (7.7)	7 (4.5)	0.263	4 (3.7)	0.253
Duration of illness, days (mean)	5.67	8.24	<0.001	8.11	0.900
GCS (mean)	11.95			12.5	0.045
Meningeal Signs	26 (38.8)	100 (63.7)	0.002	66 (59.5)	0.035
Seizure	7 (10.4)	22 (14.1)	0.287	22 (20)	0.085
Leukocytosis (WBC ≥ 12000)	28 (43.1)	51 (32.5)	0.134	39 (35.1)	0.295
ESR (mean)	41.95	30.34	0.290	34.89	0.157
Hyponatremia (Na < 135)	11 (16.4)	32 (20.5)	0.477	23 (20.9)	0.462
In Hospital Mortality	17 (25.4)	20 (12.7)	0.028	19 (18.6)	0.198

HTN/IHD: hypertension/ischemic heart disease; CVA: cerebrovascular accident; GCS: Glasgow Coma Scale; FNDs: focal neurologic deficit; WBC: white blood cell; ESR: erythrocyte sedimentation rate.