Higher vs. Lower DP for Ventilated Patients with Acute Respiratory Distress Syndrome: A Systematic Review and Meta-Analysis

Table 1

Characteristics of the studies included in the meta-analysis.

Study	Study; design	Country	Setting	Population	Sample; Size	Male; (%)	Age; (years)	Mortality; (%)	Cut-off value; (cmH20)	Follow-up; (days)
Amato et al.; 2015	ROS	Brazil	ICU	Mild to Severe ARDS	3562	NR	NR	34.7	15	Mortality at day 60
Chiu et al. 2017	ROS	Taiwan	ICU	Severe ARDS with ECMO	158	68.4	50.3	55.1	21	ICU mortality
Chiumello et al. 2016	POS	Italy	ICU	Mild to Severe ARDS	150	68	62	32	15	ICU mortality
Guerin et al. 2016	POS	France	ICU	Moderate to severe ARDS	787	68.9	59	32.3	13	Mortality at day 90
Laffey et al; . 2016	POS	Canada	ICU	Mild to severe ARDS	2377	61.9	60.5	40.1	14	Hospital mortality
Raymondos et al. 2017	POS	Germany	ICU	Mild to Severe ARDS	198	71.7	59/62.8	57.5	NR	Hospital mortality
Villar et al. 2017a	ROS	Spain	ICU	Moderate to Severe ARDS	478	69.9	54	42.2	19	Hospital mortality
Villar et al. 2017b	ROS	Spain	ICU	Moderate to Severe ARDS	300	67	57	42.3	19	Hospital mortality

ICU=intensive care unit, ARDS=acute respiratory distress syndrome, NR=not reported, ROS= retrospective observational study, ECMO=extracorporeal membrane oxygenation, POS= prospective observational study.