Trypanosome Prereplication Machinery: A Potential New Target for an Old Problem

<table>Schematic representation of the prereplication machinery from mammals (A) and trypanosomatids (B). (a) and (b) indicate the two possible mechanisms for MCM recruitment to the replication origin. (a) Orc1/Cdc6 recruits the MCM complex. (b) An unknown protein recruits the MCM complex to the replication origin.</table>

Enzyme Research

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Figure 1

Figure 1: Trypanosome Prereplication Machinery: A Potential New Target for an Old Problem 