Enolase: A Key Player in the Metabolism and a Probable Virulence Factor of Trypanosomatid Parasites—Perspectives for Its Use as a Therapeutic Target

<table>Cartoon view of <i>T. brucei </i>enolase in complex with the enolase inhibitor phosphonoacetohydroxamate (PAH; PDB code 2ptz [<a href="/journals/er/2011/932549/#B49">50</a>]). Secondary structure is coloured blue (<i><i>α</i></i>-helices), green (<i><i>β</i></i>-strands) or purple (loops) with the N-terminal domain to the right of the figure drawn in darker hues. Ligand is shown as sticks and bound metals as isolated spheres. The putative plasminogen-binding site is shown in orange.</table>

Enzyme Research

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Figure 2: Enolase: A Key Player in the Metabolism and a Probable Virulence Factor of Trypanosomatid Parasites—Perspectives for Its Use as a Therapeutic Target 

Figure 2 | Enolase: A Key Player in the Metabolism and a Probable Virulence Factor of Trypanosomatid Parasites—Perspectives for Its Use as a Therapeutic Target 