A Guided Tour of the Structural Biology of Gaucher Disease: Acid-β-Glucosidase and Saposin C

Table 2

Structures of saposin C.

PDB code	Enzyme source	Detergent?	Technique	Experimental summary	Citation
1M12	E. coli	No	NMR	^15N, ^1H, and ^13C heteronuclear NMR experiments	[45]
1SN6	E. coli	Yes, SDS	NMR	^15N, ^1H, and ^13C heteronuclear NMR experiments	[75]
2GTG	E. coli	No	Crystallography	Calcium chloride, Hepes buffer pH 7 or cacodylate buffer pH 6, glycerol cryoprotectant	[78]
2QYP	P. pastoris	No	Crystallography	Magnesium sulfate or ammonium sulfate, acetate buffer pH 4, pentaerythritol ethoxylate 15/4	[50]
2Z9A	P. pastoris	No	Crystallography	Same as 2QYP	[50]