Research Article

The Effect of D-(−)-arabinose on Tyrosinase: An Integrated Study Using Computational Simulation and Inhibition Kinetics

Figure 1

Computational simulations of tyrosinase and D-(–)-arabinose. (a) The binding pocket of tyrosinase was found using Pck software. Blue and white represent the pocket mouth, with the entrance colored in blue. The two red spheres indicate the two copper ions. (b) Plausible binding residues. Blue sticks indicate the pocket residues, and the two red spheres indicate the two copper ions. (c) The two forms of D-(–)-arabinose (up-form and down-form).
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(a)
731427.fig.001b
(b)
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(c)