Genetic Polymorphisms of Alcohol Dehydrogenase and Aldehyde Dehydrogenase: Alcohol Use and Type 2 Diabetes in Japanese Men

Table 4

Association of alcohol use with prediabetic condition and type 2 diabetes.

Alcohol use (mL/day)	No.		OR (95% CI)*
	Cases	Controls
Prediabetic condition†
Never use	60	238	1.00 (referent)
Past use	11	42	1.06 (0.51–2.23)
<30	137	405	1.38 (0.97–1.96)
30–59	178	451	1.56 (1.11–2.20)
≥60	167	384	1.74 (1.23–2.46)
Type 2 diabetes
Never use	21	238	1.00 (referent)
Past use	9	42	2.15 (0.89–5.15)
<30	71	405	2.05 (1.21–3.49)
30–59	70	451	1.70 (1.01–2.89)
≥60	64	384	1.81 (1.06–3.10)

CI: confidence interval; OR: odd ratio.
∗Adjusted for age, hospital, rank in the Self Defense Forces, body mass index, smoking, alcohol use, coffee intake, leisure-time physical activity, and parental diabetes mellitus.
† Including impaired fasting glucose and impaired glucose tolerance.