Clinical Study

Percentage of Deaths Attributable to Poor Cardiovascular Health Lifestyle Factors: Findings from the Aerobics Center Longitudinal Study

Table 3

Unadjusted and multivariable-adjusted PAF for each 5-year time intervala using the Aerobics Center Longitudinal Study, 1987–2003.

Unadjusted modelMultivariate-adjusted modelc
PAF595% CIPAF1095% CIPAF1595% CIPAF595% CIPAF1095% CIPAF1595% CI

Individual factor b
Smoking5%0.1%, 10%5%0.1%, 10%5%0.2%, 10%6%1%, 11%6%1%, 11%6%1%%, 11%
BMI9%−5%, 20%9%−5%, 20%8%−4%, 19%−7%−14%, 8%−7%−24%, 8%−7%−23%, 8%
Diet−9%−26%, 6%−9%−25%, 5%−8%−24%, 5%3%−13%, 16%3%−13%, 16%3%−12%, 15%
CRF7%2%, 11%6%2%, 11%6% 1%, 10%7%2%, 12%7%2%, 12%7%2%, 12%
Multiple factors
Smoking + BMI13%−1%, 24%12%−1%, 24%12%−1%, 23%−0.3%−17%, 14%−0.3%−17%, 14%−0.3%−16%, 14%
Smoking + Diet−4%−22%, 11%−4%−21%, 10%−4%−20%, 10%9%−7%, 22%9%−7%, 22%9%−7%, 21%
Smoking + CRF11%4%, 17%10%4%, 16%9% 3%, 15%13%6%, 19%13%6%, 19%13%6%, 18%
BMI + Diet4%−21%, 18%0.4%−21%, 18%0.2%−20%, 17%−4%−28%, 15%−4%−28%, 16%−4%−27%, 14%
BMI + CRF11%−2%, 22%11%−2%, 22%10%−3%, 20%1%−15%, 15%0.9%−15%, 14%0.8%−14%, 14%
Diet + CRF−4%−21%, 11%−4%−20%, 11%−4%−20%, 10%10%−5%, 23%10%−5%, 23%9%−5%, 22%

PAF: population attributable fraction; CI: confidence interval; BMI: body mass index; CRF: cardiorespiratory fitness; CVD: cardiovascular disease.
PAF value at 5th, 10th, and 15th year was denoted by PAF5, PAF10, and PAF15, respectively.
The definition of smoking, BMI, diet, CRF is the same as in Table 2.
Adjusted for age, gender, hypertension, diabetes, hypercholesterolemia, and family history of CVD.